Human papillomavirus (HPV) infections are the most common sexually transmitted infections. Most infections occur without symptoms and resolve without treatment. Most Canadians will have an asymptomatic HPV infection at some time. There are more than 200 strains of the HPV virus. Most HPV infections, including those that cause cancer, typically resolve within 12 months. HPV can cause anogenital warts. HPV infection is related to 80-90% of anal cancers, 40% of vaginal and vulvar cancer, 40-50% of penile cancers, and 25-35% of mouth and throat cancers. Most of these cancers are related to high-Risk HPV types 16 and 18.